tev-cosmetic-talc-general-14

Talc Evidence Atlas — release-gated evidence record. Status: verified · Track: marketing · Modified 2026-08-13

The record

In the African American Cancer Epidemiology Study (AACES), genital powder use was associated with increased epithelial ovarian cancer risk among African American women: OR = 1.44 (95% CI, 1.11-1.86), with a dose-response relationship for duration of use and lifetime applications (P < 0.05).

Claim scope

THIS IS THE STUDY McTIERNAN MEANT by 'One focused only on black women.' Verified per-record: Schildkraut JM et al., Cancer Epidemiol Biomarkers Prev 2016;25(10):1411-1417, DOI 10.1158/1055-9965.EPI-15-1281, PMC5050086. 584 cases and 745 controls, African American women, 11 US locations. It is the single strongest race-specific quantitative source available for this page.

What this source does not establish

A 44% increase, not a 50% increase. It is a case-control study and therefore subject to recall bias. It does not measure asbestos exposure — the exposure is 'genital powder use,' with no compositional analysis of the products used.

Limitations

McTIERNAN TESTIMONY CORRECTION: she testified this study found 'increased risk of at least 50 percent for ever use.' The published point estimate for genital powder use is OR 1.44 (95% CI 1.11-1.86) — a 44% increase, not 'at least 50 percent.' The CI upper bound reaches 1.86 and the nongenital nonserous estimate is 2.28, so a 50% figure is inside the range of results, but the page must report 1.44 (1.11-1.86) verbatim and must NOT repeat 'at least 50 percent' as the study's finding.

Source

Pmid — 27197282

Read the primary source