tev-cosmetic-talc-general-31

Talc Evidence Atlas — release-gated evidence record. Status: verified · Track: reconciliation:regulatory · Modified 2026-08-13

The record

The 2024 Journal of Clinical Oncology Sister Study analysis (PMID 38748950) reported a hazard ratio of 1.40 (95% CI 1.04-1.89) for genital talc use and ovarian cancer under one bias-correction scenario (25%/10% exposure reassignment); across correction scenarios the estimates ranged from 1.17 to 3.34.

Claim scope

The published bias-corrected estimates and their scenario structure.

What this source does not establish

The 1.40 figure is one bias-correction scenario, not the study's single headline result, and the 1.17-3.34 range spans correction scenarios — not exposure levels or dose categories.

Limitations

Describe the scenario structure explicitly whenever the 1.40 or the range is cited.

Source

Pmid — 38748950

Read the primary source